Anti-voltage-gated potassium channel complex antibody-mediated limbic encephalitis:a case report of a 53-yearold man admitted to intensive care psychiatric unit with psychotic mania

作     者：Homayun Shahpesandy Rosemary Mohammed-Ali Ahmed Oladosu Tarik AI-Kubaisy Moses Anene Umesh Sira Ramaiah Homayun Shahpesandy;Rosemary Mohammed-Ali;Ahmed Oladosu;Tarik Al-Kubaisy;Moses Anene;Umesh Sira Ramaiah

作者机构：The Hartsholme CentreLincolnshire Partnership NHS Foundation TrustLincolnUK Spalding Community Mental Health TeamLincolnshire Partnership NHS Foundation TrustSpaldingUK Early Intervention Psychosis Team Consultant PsychiatristNorth Lincolnshire Community Mental HealthRotherham Doncaster NHS Foundation TrustScunthorpeUK Peter Hodgkinson CentreLincolnshire Partnership NHS Foundation TrustLincolnUK Psychiatric Liaison TeamLincolnshire Partnership NHS Foundation TrustLincolnUK 

出 版 物：《General Psychiatry》 (综合精神医学（英文）)

年 卷 期：2020年第33卷第4期

页      面：241-244页

核心收录：

学科分类：1002[医学-临床医学] 100205[医学-精神病与精神卫生学] 10[医学] 

主　　题：initially potassium admitted 

摘      要：Limbic encephalitis represents a cluster of autoimmune disorders,with inflammation in the medial temporal lobe characterised by subacute onset of neuropsychiatric symptoms such as anxiety,affective symptoms,psychosis,short-term memory impairment as well as faciobrachial and grand mal *** aim to present a case of a 53-year-old man with positive anti-voltage-gated potassium channel(VGKC)complex antibodies who initially presented with symptoms of psychotic *** weeks post-psychiatric symptomatology,he presented with neurological symptoms such as faciobrachial jerking and tonic-clonic *** patient had no previous psychiatric history and was initially treated with psychotropic *** experience emphasises the fact that limbic encephalitis is not easy to identify as most patients initially present with psychiatric symptomatology than neurological ***,immunological and laboratory testing takes a rather long time to determine the *** is more,few psychiatrists consider autoimmune nature of the neuropsychiatric ***,it is important to consider autoimmune encephalitis in patients with new-onset psychosis or mania who also present with neurological symptoms at some stage of their *** indicators of autoimmune encephalitis include neurological symptoms such as facial twitching,seizures,confusion and cognitive decline.