Clinical outcomes of sacral neuromodulation in non-neurogenic,non-obstructive dysuria:A 5-year retrospective,multicentre study in China

作     者：Ling-Feng Meng Wei Zhang Jian-Ye Wang Yao-Guang Zhang Peng Zhang Li-Min Liao Jian-Wei Lv Qing Ling Zhong-Qing Wei Tie Zhong Zhi-Hui Xu Wei Wen Jia-Yi Li De-Yi Luo 

作者机构：Department of UrologyBeijing HospitalNational Center of GerontologyBeijing 100730China Department of UrologyBeijing Chaoyang HospitalInstitute of UrologyCapital Medical UniversityBeijing 100000China Department of UrologyChina Rehabilitation Research CentreRehabilitation School of Capital Medical UniversityBeijing 100000China Department of UrologySouth CampusRenji HospitalShanghai Jiao Tong University School of MedicineShanghai 200000China Department of UrologyTongji HospitalHuazhong University of Science and TechnologyWuhan 430000Hubei ProvinceChina Department of UrologyThe Second Affiliated Hospital of Nanjing Medical UniversityNanjing 210000Jiangsu ProvinceChina Department of UrologyThe Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710000Shaanxi ProvinceChina Department of UrologyZhejiang Provincial People’s HospitalHangzhou 310000Zhejiang ProvinceChina Department of UrologyShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200000China Department of UrologyRenji HospitalShanghai Jiao Tong University School of MedicineShanghai 200000China Department of UrologyWest China HospitalSichuan UniversityChengdu 610000Sichuan ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2020年第8卷第12期

页      面：2494-2501页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：Supported by National Key Research and Development Program of China No.2018YFC2002202 

主　　题：Dysuria Implanted pulse generator Non-neurogenic Non-obstructive Sacral neuromodulation 

摘      要：BACKGROUND Management of non-neurogenic,non-obstructive dysuria represents one of the most challenging dilemmas in urological *** main clinical symptom is the increase in residual *** dysfunction is the main cause of dysuria or urinary retention,mainly due to the decrease in bladder contraction(the decrease in contraction amplitude or duration)or the increase in outflow tract *** neuromodulation(SNM)has been used for10 years to treat many kinds of lower urinary tract *** has become increasingly popular in China in recent ***,studies focusing on nonneurogenic,non-obstructive dysuria patients treated by SNM are highly *** To assess the outcome of two-stage SNM in non-neurogenic,non-obstructive *** Clinical data of 54 patients(26 men,28 women)with non-neurogenic,nonobstructive dysuria treated by SNM from January 2012 to December 2016 in ten medical centers in China were retrospectively *** patients received two or more conservative *** voiding diary,urgency score,and quality of life score before operation,after implantation of tined lead in stage I(test period),and during short-term follow-up(latest follow-up)after implantation of the implanted pulse generator in stage II were compared to observe symptom *** Among the 54 study patients,eight refused to implant an implanted pulse generator because of the unsatisfactory effect,and 46 chose to embed the implanted pulse generator at the end of stage *** conversion rate of stage I to stage II was 85.2%.The average follow-up time was 18.6 *** were significant differences between baseline(before stage I)and the test period(after stage I)in residual urine,voiding frequency,average voiding amount,maximum voiding amount,nocturia,urgency score,and quality of life *** residual urine and urgency score between the test period and the latest follow-up time(after stage II)were also significantly different