Coronavirus disease 2019(COVID-19):a clinical update
作者机构：National Research Center for Translational MedicineRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200025China Department of Respiratory and Critical Care MedicineRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200025China Institute of Respiratory DiseasesShanghai Jiao Tong University School of MedicineShanghai 200025China Research Laboratory of Clinical VirologyRuijin Hospital and Ruijin Hospital North Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200025China
出 版 物：《Frontiers of Medicine》 (医学前沿（英文版）)
年 卷 期：2020年第14卷第2期
页 面：126-135页
核心收录：
基 金：funded in part by a grant from innovative research team of high-level local universities in Shanghai
主 题：coronavirus disease 2019 epidemiology pathology radiology clinical characteristics treatment
摘 要：Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)has posed a significant threat to global health.It caused a total of 80868 confirmed cases and 3101 deaths in Chinese mainland until March 8,2020.This novel virus spread mainly through respiratory droplets and close contact.As disease progressed,a series of complications tend to develop,especially in critically ill patients.Pathological findings showed representative features of acute respiratory distress syndrome and involvement of multiple organs.Apart from supportive care,no specific treatment has been established for COVID-19.The efficacy of some promising antivirals,convalescent plasma transfusion,and tocilizumab needs to be investigated by ongoing clinical trials.
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