Potential impact of epidural labor analgesia on the outcomes of neonates and children

作     者：Zhi-Hua Liu Dong-Xin Wang Liu Zhi-Hua;Wang Dong-Xin

作者机构：Department of Anesthesiology and Critical Care MedicinePeking University First HospitalBeijing 100034China. 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2020年第133卷第19期

页      面：2353-2358页

核心收录：

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

主　　题：Epidural labor analgesia Neonates Children Outcomes 

摘      要：This review summarizes recent evidences regarding the potential influences of epidural labor analgesia(ELA)on the outcomes of neonates and *** and relevant words including“ELA,“ELA and neonatal outcomes,“ELA and children’s development,and“ELA and children’s neurocognitive developmentwere used to search articles published in PubMed database up to October *** articles and reviews regarding potential influences of ELA on neonates and children were *** references of the selected articles were also *** anesthetics used during ELA can be absorbed,enter the fetus,and produce neonatal depression;however,these effects are less severe than those during systematic opioid *** impact of anesthetic exposure during ELA on children’s neurodevelopment has not been fully studied,but would be mild if *** increases the risk of intrapartum maternal fever;the latter may be harmful to neonatal *** use of ELA may increase birth injury by increasing instrumental delivery,although long-term adverse events are *** the other hand,ELA may reduce maternal depression and,thus,produce favorable effects on neurocognitive development in childhood;but evidences are still lacking in this *** may produce both favorable and unfavorable effects on neonates and *** effects should be discussed with parturient women before making *** potential harmful effects should be carefully *** overall impacts of ELA on neonatal and children’s outcomes need to be studied further.