Clinical value of ^(18)F-FDG PET/CT in assessing suspicious relapse after rectal cancer resection
Clinical value of ^(18)F-FDG PET/CT in assessing suspicious relapse after rectal cancer resection作者机构：Long Sun Wei-Min Pan Zuo-Ming Luo Ji-Hong Wei Long Zhao Hua Wu Minnan PET Center and Department of Nuclear Medicine the First Hospital of Xiamen University Xiamen 316003 Fujian Province China.
出 版 物：《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志（英文版）（电子版）)
年 卷 期：2009年第1卷第1期
页 面：55-61页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：18F-fluorodeoxyglucose Positron emission tomography/computed tomography Rectal cancer Follow-up Restaging Locoregional recurrence Distant metastases
摘 要：AIM:To evaluate the value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG PET/CT) in the restaging of resected rectal ***:From January 2007 to Sep 2008,21 patients who had undergone curative surgery resection for rectal carcinoma with suspicious relapse in conventional imaging or clinical findings were retrospectively enrolled in our *** patients underwent 28 PET/CT scans(two patients had two scans,one patient had three and one had four scans).Locoregional recurrences and/or distant metastases were confirmed by histological analysis or clinical and imaging ***:Final diagnosis was confirmed by histopathological diagnosis in 12 patients(57.1) and by clinical and imaging follow-up in nine patients(42.9).Eight patients had extrapelvic metastases with no evidence of pelvic *** patients had both pelvic recurrence and extrapelvic metastases,and two patients had pelvic recurrence only.18F-FDG PET/CT was negative in two patients and positive in 19 patients.18F-FDG PET/CT was true positive in 17 patients and false positive in *** accuracy of 18F-FDG PET/CT was 90.5,negative predictive value was 100,and positive predictive value was *** patients with perirectal recurrence underwent 18F-FDG PET/CT image guided tissue core biopsy.18F-FDG PET/CT also guided surgical resection of pulmonary metastases in three patients and monitored the response to salvage chemotherapy and/or radiotherapy in four ***:18F-FDG PET/CT is useful for evaluating suspicious locoregional recurrence and distant metastases in the restaging of rectal cancer after curative resection.
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