Removal of biofilm is essential for long-term ventilation tuberetention
作者机构：Department of Otorhinolaryngology–Head&Neck Surgerythe Sixth People’s Hospital Affiliated to Shanghai Jiaotong UniversityShanghai 200233China Shanghai Key Laboratory of Sleep Disordered BreathingShanghai 200233China
出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)
年 卷 期：2020年第8卷第9期
页 面：1592-1599页
核心收录：
学科分类：1002[医学-临床医学] 100213[医学-耳鼻咽喉科学] 10[医学]
基 金：Supported by Shanghai Leadership Talent Training Plan,No. 2017062 the Key Project of Shanghai Jiao Tong University Medicine Science and Engineering Interdisciplinary Foundation,No. YG2016ZD02 Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support,No.20152233 Multi-Center Clinical Research Plan of Medical College of Shanghai Jiao Tong University,No. DLY201823 the Clinical Research Plan of Shanghai Shen Kang Hospital Development Center,No. 16CR4022A and No.16CR3041A National Natural Science Foundation of China,No.81974142
主 题：Tympanostomy tubes Biofilm Complication management Long-term retention Ménière disease Refractory otitis media with effusion
摘 要：BACKGROUND Although long-term retention of a ventilation tube is required in many ear diseases,spontaneous removal of conventional ventilation tube is observed in patients within 3 to 12 *** address this issue,we aimed to determine a new method for long-term retention of the ventilation *** To explore the value of removing the biofilm for long-term retention of tympanostomy ventilation *** A case-control study design was used to evaluate the safety and effectiveness of long-term tube retention by directly removing the biofilm(via surgical exfoliation)in patients who underwent myringotomy with ventilation tube *** patients were randomly divided into two groups:Control group and treatment *** in the treatment group underwent regular biofilm exfoliation surgery in the clinic,whereas those in the control group did not have their biofilm *** conventional ventilation tubes were placed in this *** measures were tube position and *** retention time and any complications were *** Eight patients with biofilm removal and eight patients without biofilm removal as a control group were enrolled in the *** tympanostomy tube retention time was significantly longer in the treatment group(43.5±26.4 mo)than in the control group(9.5±6.9 mo)(P=0.003).More tympanostomy tubes were found to be patent and in correct position in the treatment group during the follow-up intervals than in the control group(P=0.01).CONCLUSION Despite the use of short-term ventilation tubes,direct biofilm removal can be a well-tolerated and effective treatment for long-term tube retention of tympanostomy ventilation tubes in patients who underwent myringotomy.
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