Antioxidant and antibacterial activities and identification of bioactive compounds of various extracts of Caulerpa racemosa from Algerian coast

作     者：Louiza Belkacemi Mahmoud Belalia Ali C.Djendara Youcef Bouhadda Louiza Belkacemi;Mahmoud Belalia;Ali C. Djendara;Youcef Bouhadda

作者机构：Laboratoire de Technologie Alimentaire et de NutritionSite II EX-INES de ChimieChemin des CrêtesBP 188Abdelhamid IbnBadis UniversityMostaganemAlgeria Laboratoire de StructureElaboration et Application des Matériaux MoléculairesSite II EX-INES de ChimieChemin des CrêtesBP 188Abdelhamid IbnBadis UniversityMostaganemAlgeria Laboratoire de Chimie Physique des Biomolécules et Interfaces BiologiquesB.P.305Route de MamouniaMustapha Stambouli University MascaraAlgeria 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2020年第10卷第2期

页      面：87-94页

核心收录：

学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1007[医学-药学(可授医学、理学学位)] 10[医学] 

主　　题：Caulerpa racemosa var.cylindracea West Algerian coast Biological activities Clionasterol 4-Hydroxy-2methylproline 

摘      要：Objective:To evaluate the antibacterial and antioxidant activities and to identify the volatile bioactive compounds present in different crude extracts of the seaweed Caulerpa racemosa ***:Caulerpa racemosa harvested from the intertidal zone of Mostaganem coast(N 35?54’37.94,E 0?3’17.37)was subjected to Soxhlet extraction using methanol,chloroform,and hexane *** properties were assessed by using 2,2’-diphenyl-1-picrylhydrazyl(DPPH),2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)(ABTS)andβ-carotene bleaching *** antibacterial activity was evaluated on six standard bacterial strains using the agar disc diffusion *** GC-MS analysis was performed using non-polar and polar capillary ***:The chloroform extract of Caulerpa racemosa exhibited higher contents of polyphenols[(123.91±1.46)mg gallic acid equivalent/g dry extract]and tannins[(59.28±5.43)mg catechin equivalent/g dry extract](P0.001)and was the most effective in scavenging DPPH[(1.98±0.08)mg/m L]and ABTS[(1.66±0.05)mg/m L]*** hexane extract displayed the best antibacterial activity against Staphylococcus aureus,Bacillus cereus,and Pseudomonas aeruginosa,producing inhibition zones of(11.16±0.76),(9.00±0.00)and(9.33±1.15)mm,*** l-(+)-ascorbic acid 2,6-dihexadecanoate and 4-hydroxy-2 methylproline were among the most abundant volatile *** conventional fatty acids,cis-10-heptadecenoic acid,nonahexacontanoic acid,and dodecanoic acid,3-hydroxy-were *** phytosterols were identified:stigmast-5-en-3-ol-(12.9%)and ***.-ol,(24 S)-(4.57%).Conclusions:The preliminary identification of the volatile compounds reveals the presence of some new bioactive components not reported previously in Caulerpa racemosa from other geographical *** of these compounds possess an interesting potential for pharmaceutical/nutraceutical applications.