Erectile dysfunction and statins: The assorted view of preponderance
作者机构：Department of PharmacologyToxicology and MedicineCollege of MedicineAlmustansiriya UniversityBaghdadIraq
出 版 物：《Asian pacific Journal of Reproduction》 (亚太生殖杂志（英文版）)
年 卷 期：2020年第9卷第2期
页 面：55-63页
学科分类：08[工学] 0812[工学-计算机科学与技术（可授工学、理学学位）]
主 题：Erectile dysfunction Statins Testosterone
摘 要：Objective:To explore the association between statin therapy and the risk of erectile dysfunction by literature ***:We conducted diversities of search strategies including electronic database searches of MEDLINE,Scopus,Pubmed and Web of Science using MeSH terms,keywords and title words during the *** lists of identified and public articles were *** addition,only English articles were considered and case reports were not concerned in the *** key features of recognized applicable search studies were considered and the conclusions were summarized in a narrative ***:Different studies gave a consensus that erectile dysfunction was regarded as an early sign of silent cardiovascular disorder and hidden *** studies reported that statins might induce erectile dysfunction through induction of peripheral neuropathy,cognitive deficits,and reduction of circulating ***,most of recent studies illustrated that statins led to a significant improvement in erectile function and sexual health in men with age over forty *** advanced endothelial nitric oxide concentrations through activation and upregulation of endothelial nitric oxide synthase and rescued phosphodiesterase-5 inhibitors non-responders since nitric oxide and cyclic guanosine monophosphate increased penile blood flow and improved erectile ***:According to the assorted view of preponderance,statins improved erectile dysfunction is more dominant than statins induced erectile ***,statins regardless of its property improve erectile dysfunction through amelioration of penile endothelial dysfunction,and penile neuronal reflexes that are inter-related during sexual excitation and penile erection.
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