White esophageal lesions in a patient with scleroderma:epidermoid metaplasia

作     者：Matthew Woo Emma Whitcomb Dorothy Li Sandra Lee Michael Curley 

作者机构：Division of GastroenterologyDepartment of MedicineUniversity of CalgaryCalgaryAlbertaCanada Alberta Laboratory ServicesDepartment of Pathology and Laboratory MedicineUniversity of CalgaryCalgaryAlbertaCanada 

出 版 物：《Gastroenterology Report》 (胃肠病学报道（英文）)

年 卷 期：2020年第8卷第2期

页      面：161-163,I0003页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：esophageal Barrett esophagus 

摘      要：Case presentation We report the case of a 67-year-old female with a 24-year smoking history who initially underwent esophagogastroduodenoscopy(EGD)in 2012 for gastroesophageal reflux disease(GERD),which demonstrated short-segment Barrett’s esophagus without *** EGD 6 years later showed severe reflux esophagitis(LA grade D).She was subsequently diagnosed with limited systemic sclerosis(CREST syndrome)on the basis of Raynaud’s disease,sclerodactyly,telangiectasias,seropositivity(anti-CENP-A,anti-CENP-B),and pulmonary ***-resolution esophageal manometry showed esophageal body aperistalsis with a hypotensive lower esophageal sphincter(LES)(Figure 1).