The effects of Spirulina on anemia and immune function in senior citizens
作者机构：Division of RheumatologyAllergy and Clinical ImmunologyUniversity of California at DavisDavisCAUSA Department of MedicineIRCCS Istituto Clinico HumanitasRozzanoMilanItaly Department of Food Science and TechnologyUniversity of California at DavisDavisCAUSA CyanotechKailua-KonaHIUSA
出 版 物：《Cellular & Molecular Immunology》 (中国免疫学杂志（英文版）)
年 卷 期：2011年第8卷第3期
页 面：248-254页
核心收录：
学科分类：0710[理学-生物学] 071001[理学-植物学] 07[理学]
主 题：functional food immunosenescence red blood cell IDO
摘 要：Anemia and immunological dysfunction(***)are commonly found in older subjects and nutritional approaches are sought to counteract these *** is a filamentous and multicellular bule-green alga capable of reducing inflammation and also manifesting antioxidant *** hypothesized that Spirulina may ameliorate anemia and immunosenescence in senior citizens with a history of *** enrolled 40 volunteers of both sexes with an age of 50 years or older who had no history of major chronic *** took a Spirulina supplementation for 12 weeks and were administered comprehensive dietary questionnaires to determine their nutritional regimen during the *** cell count(CCC)and indoleamine 2,3-dioxygenase(IDO)enzyme activity,as a sign of immune function,were determined at baseline and weeks 6 and 12 of *** study participants completed the entire study and the data obtained were *** the 12-week study period,there was a steady increase in average values of mean corpuscular hemoglobin in subjects of both *** addition,mean corpuscular volume and mean corpuscular hemoglobin concentration also increased in male *** women appeared to benefit more rapidly from Spirulina ***,the majority of subjects manifested increased IDO activity and white blood cell count at 6 and 12 weeks of Spirulina *** may ameliorate anemia and immunosenescence in older *** encourage large human studies to determine whether this safe supplement could prove beneficial in randomized clinical trials.
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