Lack of Corneal Toxicity of Interferon Alpha-2b Administered Subconjunctivally after Sclerectomy
Lack of Corneal Toxicity of Interferon Alpha-2b Administered Subconjunctivally after Sclerectomy作者机构：Zhongshan Ophthalmic Center Sun Yat-sen University of Medical Sciences Guangzhou 510060 China.
出 版 物：《眼科学报》 (Eye Science)
年 卷 期：1997年第13卷第1期
页 面：35-37页
学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
摘 要：Purpose: To evaluate the corneal toxicity of subconjunctival injection interferon α-2bat filtering bleb after sclerectomy in white ***: Eight rabbits which had been performed sclerectomy were randomlydivided into two groups. Each group consisted of four rabbits. Eight eyes in group 1were subconjunctivally received interferon α-2b 5 × 105IU/0. 2ml into filtering blebfrom the edge of the filtering site immediately after operation and every postoperativeday. The other eight eyes in group 2 were injected with 0. 2ml normal saline. All ofthe eyes underwent daily examination by slip-lamp microscopy and directophthalmoloscopy. Sodium fluorescein was used to assess corneal epithelial *** day 3,4,7 and 14, every two rabbits (group 1 and 2 each, respectively) werekilled and removed cornea immediately to take examination of the viability of cornealendothelium by dual staining with typan blue and alizanin red ***: No sign of toxicity in corneal epithelium and endothelium were
维普期刊数据库
同方期刊数据库