Piezo-/ferroelectric phenomena in biomaterials: A brief review of recent progress and perspectives

作     者：Yao Sun KaiYang Zeng Tao Li Yao Sun;KaiYang Zeng;Tao Li

作者机构：Department of Mechanical EngineeringNational University of SingaporeSingapore 546080Singapore Center for Spintronics and Quantum SystemsState Key Laboratory for Mechanical Behavior of MaterialsSchool of Materials Science and EngineeringXi'an Jiaotong UniversityXi'an 710049China 

出 版 物：《Science China(Physics,Mechanics & Astronomy)》 (中国科学：物理学、力学、天文学（英文版）)

年 卷 期：2020年第63卷第7期

页      面：29-46页

核心收录：

学科分类：071011[理学-生物物理学] 0710[理学-生物学] 07[理学] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：supported by the Ministry of Education (Singapore) through the National University of Singapore under the Academic Research Grant (ACRF) (Grant Nos. R-265-000-495-112, and R-265-000-596-112) financial support from the National Key Research and Development Program of China (Grant Nos. 2018YFB0407600, 2017YFA0206202, and 2016YFA0300702) the National Natural Science Foundation of China (Grant No. 51802250) the Key Research and Development Program of Shaanxi (Grant No. 2019TSLGY0804) 

主　　题：biomaterials electromechanical coupling piezoelectric ferroelectric piezoresponse force microscopy 

摘      要：There have been overwhelming observations of piezo-/ferroelectric phenomena in many biological tissues and macromolecules,boosting the development of bio-based smart devices and the applications using electromechanical coupling phenomena in biological *** electromechanical coupling is believed to be responsible for various biophysical behaviors and remarkable biomaterial *** the abundant phenomenal observations,the fundamental understanding of the piezo-/ferroelectric effect in biomaterials/systems and the rational design of biobased macroscopic materials with desired piezoelectric responses are still *** this review,we firstly present remarkable historical events on the development of piezo-/ferroelectricity in biomaterials,followed by a brief overview of the fundamental physics of piezo-/*** developments of biopiezo-/bioferroelectricity in protein-based biomaterials and their implications are highlighted *** experimental studies,to identify the intrinsic piezo-/ferroelectric properties from other effects or artifacts is usually *** issue is also addressed and discussed in detail,especially using piezoelectric force microscopy(PFM)and spectroscopy techniques to investigate the local piezo-/ferroelectric phenomena in nanostructured materials are highlighted emphatically.