Clinical utility of characterizing intestinal flora in septic kidney injury
Clinical utility of characterizing intestinal flora in septic kidney injury作者机构:Department of Critical CareLanzhou University Second HospitalLanzhouGansu 730030China
出 版 物:《Chinese Medical Journal》 (中华医学杂志(英文版))
年 卷 期:2020年第133卷第7期
页 面:842-846页
核心收录:
学科分类:1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金:supported by a grant from the Scientific Research Program of the Health Industry Gansu Province China(No.GSWSKY-2014-32)
主 题:Intestinal flora Kidney injury Sepsis
摘 要:The incidence of septic acute kidney injury(AKI)is increasing,it has become a major threat to human health because of its acute onset,poor prognosis,and high hospital *** most common cause of AKI in critical-care units is *** AKI is a complex and multi-factorial process;its pathogenesis is not fully *** sepsis,the destruction of mucosal barriers,intestinal flora disorders,intestinal ischemia/reperfusion injury,use of antibiotics,and lack of intestinal nutrients lead to an inflammatory reactions that in turn affects the metabolism and immunity of the *** changes further influence the occurrence and development of *** technology is enabling various detection methods for intestinal *** application of these methods in septic renal injury is expected to clarify the relationship among pathogenesis,disease progression mechanism,and intestinal flora.