Same Concept Different Outcomes:Sugars Determine Circadian Clock Protein Fate in Animals and Plants

作     者：Wei Liu Joshua M.Gendron Wei Liu;Joshua M.Gendron

作者机构：Department of MolecularCellular and Developmental BiologyYale UniversityNew HavenCT 06511USA 

出 版 物：《Molecular Plant》 (分子植物（英文版）)

年 卷 期：2020年第13卷第3期

页      面：360-362页

核心收录：

学科分类：0710[理学-生物学] 071001[理学-植物学] 07[理学] 

基　　金：supported by the Forest B.H.and Elizabeth D.W.Brown Fund,National Science Foundation(EAGER#1548538 and IOS#1856452) National Institutes of Health(R35 GM128670) 

主　　题：maintain oscillator precise 

摘      要：Most eukaryotes have a self-sustaining circadian clock that senses environmental cues and the internal metabolic state and then imposes daily temporal organization of the *** clock,by nature,regulates the daily creation and destruction of a large quantity of RNA and proteins,including those at the core of the oscillator *** a transcriptional-translational feedback loop maintains the rhythmicity of the oscillator,various post-translational modifications(PTMs)of clock proteins play fundamental roles in keeping the pace of the circadian clock near 24 *** maintain circadian clock pacing,PTMs act to ensure the rapid,efficient,and precise activation,inactivation,and finally destruction of core clock proteins(Hirano et al.,2016).