Recent progress in microRNA study:Benefits from technique advance

作     者：YU Jia WANG Fang 

作者机构：Department of Biochemistry and Molecular Biology National Laboratory of Medical Molecular Biology Peking Union Medical College & Chinese Academy of Medical Sciences Beijing 100005 China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2012年第55卷第7期

页      面：649-650页

核心收录：

学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 071007[理学-遗传学] 

主　　题：小分子RNA 技术进步 蛋白编码基因 非编码RNA 基因组测序 miRNA 细胞功能 微RNA 

摘      要：Over the last decade, sequencing of different genomes re- vealed that an increase in organismal complexity is not merely explained by a dramatic increase in the number of protein-coding genes. However, the gradual increase in protein diversity contributes a lot to the complexity of high- er organisms [1]. It is now widely accepted that non-coding RNAs （ncRNAs）, especially microRNAs （miRNAs） largely define eukaryotic cell functions and the impacts of a variety of gene regulation [2].