Prevalence of human herpesvirus 8 infection in patients undergoing hemodialysis using nested-PCR

作     者：Somayeh Shokri Shahab Mahmoudvand Manoochehr Makvandi Toran Shahani AliSamadi Heshmatollah Shahbazian 

作者机构：Student Research CommitteeAhvaz Jundishapur University of Medical SciencesAhvazIran Department of VirologySchool of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran Department of AnatomySchool of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran Department of NephrologyDialysis and Kidney TransplantationAhvaz Jundishapur University of Medical SciencesAhwazIran 

出 版 物：《Journal of Acute Disease》 (急性病杂志（英文版）)

年 卷 期：2019年第8卷第6期

页      面：250-254页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：This study was financially supported by Student Research Committee Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran 

主　　题：Human herpesvirus 8 Hemodialysis patients Nested-PCR 

摘      要：Objective:To study the prevalence of HHV-8 infection in patients undergoing ***:In this study,blood samples of 89 patients undergoing hemodialysis were *** was extracted from peripheral blood mononuclear cells and HHV-8 DNA was evaluated by ***:Of total 89 patients,51(57.3%)were males and 38(42.7%)were *** patients age ranged from 24 to 90 years and the mean age was(57.5±1.4)***-8 DNA was found in 9 of 89(10.1%)peripheral blood mononuclear cell samples,8/51(15.7%)in males and 1/38(2.6%)in females(P=0.07).All patients who were positive for HHV8-DNA were more than 50 years ***:This study shows high prevalence of *** hemodialysis patients are candidates for kidney transplantation and due to the possibility of HHV8-reactivation and its serious complications in immunocompromised patients,routine screening for detection of the virus should be implemented for all hemodialysis patients.