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Sero-Prevalence of HBV, HCV and HEV among the Egyptian Pregnant Females

Sero-Prevalence of HBV, HCV and HEV among the Egyptian Pregnant Females

作     者:Suzan Samir Elsharkawy Wael Samir Elgazayerli 

作者机构:Lecturer at Department of Obstetrics and Gynecology Faculty of Medicine Alexandria University Alexandria Egypt 

出 版 物:《Open Journal of Obstetrics and Gynecology》 (妇产科期刊(英文))

年 卷 期:2019年第9卷第10期

页      面:1429-1438页

学科分类:1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主  题:Viral Hepatitis Hepatitis B Virus Hepatitis C Virus Hepatitis E Virus Pregnant Women 

摘      要:Background: Viral hepatitis in pregnant women can be caused by multiple types of hepatitis viruses and can cause a wide range of symptoms and complications, ranging from asymptomatic infection to maternal and fetal deaths. Objective: The aim of this study was to evaluate the sero-prevalence and the associated factors of viral hepatitis B (HBV), viral hepatitis C (HCV) and viral hepatitis E (HEV) among the Egyptian pregnant females. Methods: This cross-sectional study was conducted in the period from January to July 2017 in two selected antenatal clinics;El-shat by maternity university hospital at Alexandria city and El-Behera health insurance antenatal clinic at Damanhur city on 261 apparently healthy gravid women. Eligible women were evaluated by a questionnaire about socio-demographic data and viral serological tests were done at El-shat by maternity University Hospital Laboratory. Results: The overall HBs-Ag sero-prevalence in the pregnant women included in this study was 7 cases (2.7%) and HCV-RNA PCR was 4 cases (1.5%). Of the total study participants, none of them (0%) were anti-HEV IgM positive and 48 cases (18.4%) were anti-HEV IgG positive. According to our results, neither age of the woman, place of residence, past family history of hepatitis virus infection nor having a pet animal had any strong association to be considered as an associated factor for acquiring HEV infection. Conclusion: Although it seems that there are many improvements in the prevalence of different hepatitis viruses in the country, hepatitis viral infections are still high enough to continue their preventive programs and health education, to protect the mothers and their fetuses from the hazardous effects of these serious infections.

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