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Synthesis of an optically active intermediate for A-ring of 19-nor-1α,25-dihydroxyvitamin D3

Synthesis of an optically active intermediate for A-ring of 19-nor-1α,25-dihydroxyvitamin D_3

作     者:Shan Qian Li Hai Lei Tang Jin Cheng Yang Yong Wu 

作者机构:Key Laboratory of Drug Targeting and Novel Drug Delivery Systems West China School of Pharmacy Sichuan University Chengdu 610041 China 

出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))

年 卷 期:2007年第18卷第3期

页      面:261-262页

核心收录:

学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基  金:Financial support from the National Natural Science Foundation of China(No.29972013)is gratefully acknowledged 

主  题:A-ring of 19-nor-1α,25-dihydroxyvitamin D3 Intermediate Synthesis 

摘      要:An optically active intermediate 5 for A-ring of 19-nor-1α,25-dihydroxyvitamin D3 2 has been synthesized in five steps, starting from readily available, inexpensive v(+)-xylose 6 with good yield.

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