Human immunodeficiency virus and avascular necrosis of femur head: a case report

作     者：A.ATAHANCAG^ATAY REYHANKU^eCU^eKKAYA MURATAKYILDIZ HANDEBERK TANERYILDIRMAK HALITO^eZSU^eT HALUKERAKSOY SEMRACALANGU 

作者机构：DepartmentofClinicalMicrobiologyandInfectiousDiseasesIstanbulFacultyofMedicineIstanbulUniversityIstanbul80260Turkey DepartmentofInternalMedicineDivisionofHaematologyIstanbulFacultyofMedicineIstanbulUniversityIstanbul80260Turkey DepartmentofInternalMedicineIstanbulFacultyofMedicineIstanbulUniversityIstanbul80260Turkey DepartmentofClinicalBacteriologyandInfectiousDiseasesSSKEducationalHospitalofOkmeydaniIstanbul80260Turkey 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2004年第117卷第9期

页      面：1437-1440页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Avascular necrosis · antiphospholipid antibody · HIV infection · pregnancy 

摘      要：Avascular necrosis (AVN), also termed as osteonecrosis or aseptic necrosis, is a process caused by direct and indirect damage to the vascular supply of the involved bone.1-5 Clinical course of the disease is usually progressive and causes significant pain and limitation of movement. Trauma causes AVN by the obvious direct interruption of the vascular supply, but there are a variety of underlying systemic disorders associated with the development of AVN via indirect vascular compromise. The known risk factors include corticosteroid use, alcohol abuse, smoking, sickle cell anemia, coagulopathies, systemic lupus erythematosus, hypercholesterolemia, Gaucher s disease, chronic pancreatitis, and hyper-triglyceridemia.3 It is very difficult to define reasons of AVN in individual patient, because most of the patients had multiple risk factors for AVN. On the other hand, approximately 10%-20% of AVN cases have no known risk factors and are classified as idiopathic AVN.