In vitro Mineralization Behavior of the Sol-gel Derived Bioglass/Collegen Composite Porous Scaffold

作     者：陈晓峰 

作者机构：The Key Laboratory of Specially Functional Materials and Advanced Manufacturing Technology of Ministry of Education South China University of Technology Guangzhou 510640 China 

出 版 物：《Journal of Wuhan University of Technology(Materials Science)》 (武汉理工大学学报（材料科学英文版）)

年 卷 期：2005年第20卷第B12期

页      面：22-23,34页

学科分类：08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：FundedbytheNationalNaturalScienceFoundationofChina(Project50472054and50272021)theNaturalScienceFoundationProjectofGuangdong(020898and05006587) andtheProjectofScienceandTechnologyofGuangzhouProvince(2003Z1D0021) 

主　　题：collagen sol-gel bioactive glass tissue engineering scaffold hydroxyl-carbonateapatite ( HCA ) 

摘      要：The porous scaffold of the sol-gel derived bioactive glass （BG） in the system CaO-P2O5-SiO2 was treated with the type Ⅰ collagen solution. The pore walls of the scaffold were covered by the collagenous network. The in vitro mineralization behavior of the sol- gel derived bioglassl collegen composite porous scaffold was investigated by immersion in supersaturated calcification solution （ SCS ） at 37℃ for different times, XRD , FTIR, SEM/ EDAX techniques were applied to analyze the crystalline phases, morphology and composition of the minerals formed on the pore walls of the scaffold. It was found that with increasing of immersion time, the morphology of reaction products on the pore walls changed from the spherical particles of calcium phosphate to the flake-like HCA crystals.