Signal promoting role of a p-type transition metal dichalcogenide used for the detection of ultra-trace amounts of diclofenac via a labeled aptasensor

作     者：Abdolhamid Hatefi-Mehrjardi Amirkhosro Beheshti-Marnani Zarrin Es'haghi 

作者机构：Department of ChemisttryPayamc Noor University(PNU)TehranIran 

出 版 物：《Frontiers of Chemical Science and Engineering》 (化学科学与工程前沿（英文版）)

年 卷 期：2019年第13卷第4期

页      面：823-831页

核心收录：

学科分类：0817[工学-化学工程与技术] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 0703[理学-化学] 

基　　金：Payame Noor University  PNU 

主　　题：labeled aptasensor transition metal dichalcogenide graphene oxide sodium diclofenac 

摘      要：A p-type transition metal dichalcogenide(WS2)was synthesized and hybridized with graphene oxide via a simple hydrothermal *** as-prepared material was used to modify a glassy carbon electrode for the fabrication of a simple,stable,and repeatable methylene blue-labeled“signal-offaptasensor used for the sensitive determination of very low amounts of sodium diclofenac(DCF).The synthetic material,modification process,and role of WS2 in the current response enhancement were studied by X-ray diffraction,energy-dispersive X-ray spectroscopy,field emission scanning electron microscopy,high resolution transmission electron microscopy,Hall effect,cyclic voltammetry,differential pulse voltammetry,and electrochemical impedance ***,a wide linear range of DCF concentration(0.5-300 nmol/L),very low limit of detection(0.23 nmol/L),and good selectivity were obtained using the differential pulse voltammetry method with the assembled ***,the fabricated aptasensor was successfully developed for physiological real samples with significant recoveries.