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Unexpected encounter of the parasitic kind

Unexpected encounter of the parasitic kind

作     者:Holly Matthews Florian Noulin 

作者机构:Centre for Applied Entomology and Parasitology School of Life Sciences Keele University 

出 版 物:《World Journal of Stem Cells》 (世界干细胞杂志(英文版)(电子版))

年 卷 期:2019年第11卷第11期

页      面:904-919页

核心收录:

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Stem cells Parasites Transplantation Therapeutic Host pathogen interactions 

摘      要:Both parasitology and stem cell research are important disciplines in their own *** are a real threat to human health causing a broad spectrum of diseases and significant annual rates morbidity and mortality *** cell research,on the other hand,focuses on the potential for regenerative medicine for a range of diseases including cancer and regenerative *** these two topics might appear distant,there are some“unexpected encounters.In this review,we summarise the various links between parasites and stem ***,we discuss how parasites’own stem cells represent interesting models of regeneration that can be translated to human stem cell ***,we explore the interactions between parasites and host stem cells during the course of ***,we investigate from a clinical perspective,how stem cell regeneration can be exploited to help circumvent the damage induced by parasitic infection and its potential to serve as treatment options for parasitic diseases in the ***,we discuss the importance of screening for pathogens during organ transplantation by presenting some clinical cases of parasitic infection following stem cell therapy.

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