GC-MS Analysis of Amino Acids in Extract of Cornus Caprae Hircus

作     者：XU Jin-zhong SHEN Jie CHENG Yi-yu QU Hai-bin 

作者机构：Department of Chinese Medicine Science and Engineering College of Pharmaceutical Sciences Zhejiang University Hangzhou 310058 P. R. China 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)

年 卷 期：2009年第25卷第6期

页      面：812-816页

核心收录：

学科分类：0710[理学-生物学] 0832[工学-食品科学与工程（可授工学、农学学位）] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 083201[工学-食品科学] 

基　　金：Supported by the National Basic Research Program of China(No.2005CB523402) the Program for New Century Excellent Talents in University of China(No.NCET-06-0515) 

主　　题：Comus Caprae Hircus Amino acid Gas chromatography-mass spectrometry Quantification 

摘      要：Amino acids are an important type of bioactive components in Chinese traditional medicines, especially animal drugs. However, few modern analytical methods targeted at amino acids have been developed for the quality control of animal drugs. A gas chromatography-mass spectrometric method was built for the quantification analysis of amino acids in the extracts of Comus Caprae Hircus which has been widely used in Chinese medicine compound prescriptions. The full method validation, including the linearity, limit of detection and quantification, repeatability, precision, stability, and recovery test, was examined. The results indicate that the developed method is suitable for the quantification of amino acids in the extracts of Comus Caprae Hircus. The developed method was applied to the quantification analysis of twelve amino acids in different batches of extracts of Comus Caprae Hircus.