Synthesis of 1,2,3-benzotriazin-4-one derivatives containing spirocyclic indoline-2-one moieties and their nematicidal evaluation

作     者：Gao-Lei Wang Xi Chen Ya-Ning Chang Dan Du Zhong Li Xiao-Yong Xu 

作者机构：Shanghai Key Laboratory of Chemical Biology School of Pharmacy East China University of Science and Technology Shanghai Collaborative Innovation Center for Biomanufacturing Technology East China University of Science and TechnologyShanghai Key Laboratory of Chemical Biology School of Pharmacy 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2015年第26卷第12期

页      面：1502-1506页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：financial supported by the National High Technology Research and Development Program of China(National 863 Program,No.2013AA065202) the National Natural Science Foundation of China(No.21272071) supported by the Special Fund for Agro-scientific Research in the Public Interest(No.201103007) the Fundamental Research Funds for the Central Universities 

主　　题：Meloidogyne incognita displayed endowed moderate implied potent crops removed afford 

摘      要：To discover new chemotypes of nematicides with proper toxicological profiles, a series of novel 1,2,3-benzotriazin-4-one derivatives were synthesized and further bioevaluated. The bioassay results showed that most of the synthesized compounds were endowed with moderate to good control efficacy against Meloidogyne incognita at 10.0 mg/L in vivo. Among them, compounds 6k and 6p displayed 100%inhibitory activities at this concentration, which implied that they could be used as lead compounds for promising nematicides.