En bloc resection concept for endoscopic endonasal nasopharyngectomy： surgical anatomy and outcome

作     者：Hsu Ning-i Shen Ping-hung Chao Siew-shuen Ong Yew-kwang Li Cho-shun 

作者机构：Department of Otolaryngology Kuang-Tien General HospitalTaichung Taiwan China Department of Biotechnology Hung-Kuang University TaichungTaiwan China Department of Otolaryngology Head and Neck Surgery National University Hospital Singapore Department of Neurosurgery Chung-Shan Medical UniversityHospital Taichung Taiwan China School of Medicine Chung-Shan Medical University TaichungTaiwan China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2014年第127卷第16期

页      面：2934-2939页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：nasopharyngeal carcinoma nasopharyngectomy endoscopy tensor palatini muscle levator palatini muscle 

摘      要：Background Nasopharyngeal carcinoma （NPC） patients have a 19%-56% locoregional recurrence rate after primary *** those recurrent NPC （rNPC） patients,re-irradiation may cause some *** recent years,endoscopic endonasal nasopharyngectomy （EEN） has become a surgical option for rNPC *** we introduce the concept of en bloc excision （EBE） technique for EEN,including the surgical technique and clinical *** A retrospective study was conducted covering September 2009 to May 2013,involving the collection of Iocoregional rNPC cases from two institutions （Kuang-Tien General Hospital （KTGH） in Taiwan and National University Health System （NUHS） in Singapore）.These patients failed prior therapy and then underwent *** reported the 2-year overall survival rate,the 2-year disease-free survival rate,and related *** Nine patients （five from KTGH and four from NUHS） completed this study,with five,two,and two patients of recurrence tumors （rT1）,rT2,and rT3,*** mean age was 46.4 years （range 32-63）; the mean follow-up period was 24.9 months （range 10-45）.The 2-year survival rate and the 2-year disease-free rate were 100% and 80%,respectively,in five *** significant complications or cases of mortality *** The EBE concept of EEN is suitable for early rT1 and has relatively encouraging short-term *** selected rT2,careful EBE can be performed by expanding the surgical field.A clear view of the internal carotid arteryrelated anatomy is *** the future,more series may be needed to determine the role of EEN in rNPC patients.