Current pathogenetic aspects of hepatic encephalopathy and noncirrhotic hyperammonemic encephalopathy

作     者：Halina Cichoz-Lach Agata Michalak 

作者机构：Department of GastroenterologyMedical University of Lublin20094 LublinPoland 2nd Faculty of MedicineMedical University of Lublin20059 LublinPoland 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2013年第19卷第1期

页      面：26-34页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：Hepatic encephalopathy Noncirrhotic hyperammonemic encephalopathy Pathogeneses Ammonia Astrocyte Oxidative stress 

摘      要：Hepatic encephalopathy is a medical phenomenon that is described as a neuropsychiatric manifestation of chronic or acute liver disease that is characterized by psychomotor,intellectual and cognitive abnormalities with emotional/affective and behavioral *** article focuses on the underlying mechanisms of the condition and the differences between hepatic encephalopathy and noncirrhotic hyperammonemic *** encephalopathy is a serious condition that can cause neurological death with brain edema and intracranial *** is assumed that approximately 60%-80% of patients with liver cirrhosis develop hepatic encephalopathy This review explores the complex mechanisms that lead to hepatic ***,noncirrhotic hyperammonemic encephalopathy is not associated with hepatic diseases and has a completely different *** hyperammonemic encephalopathy is a severe occurrence that is connected with multiple pathogeneses.