Comparative characterization of mesenchymal stem cells from different age groups of cynomolgus monkeys

作     者：ZHANG Y.Alex 

作者机构：Cell Therapy CenterXuanwu HospitalCapital Medical Universityand Key Laboratory of NeurodegenerationMinistry of Education 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2010年第53卷第5期

页      面：563-572页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071009[理学-细胞生物学] 

基　　金：supported in part by the National High Technology Research and Development Program of China (Grant No 2006AA02A114) the Science Project of Beijing Municipal Science Technology Commission (Grant No D07050701350703) 

主　　题：cynomolgus monkey mesenchymal stem cells differentiation expansion safety 

摘      要：Bone marrow mesenchymal stem cells(BM-MSCs) are a potential tool for cell therapy and tissue *** this study,we carried on a comparative study of the characteristics of MSCs from different age cynomolgus monkeys.A variety of factors,including donor age,must be considered before further applications,and various tests should be used to properly assess MSCs before the clinical application,especially when a prolonged culture and ex vivo expansion is necessary.