对新青霉素耐药的后天免疫性群体性金色葡萄球菌导致眼眶蜂窝组织炎引发双眼失明
Bilateral blindness from orbital cellulitis cau-sed by community-acquired methicillin-resis-tant Staphylococcus aureus作者机构：Beckman Visi on Center University of California San Francisco 10 Koret Way K- 301 San Fr ancisco CA 94143- 0730 United States Dr.
出 版 物：《世界核心医学期刊文摘(眼科学分册)》 (Digest of the World Core Medical Journals)
年 卷 期：2006年第2期
页 面：26-26页
学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
主 题：双眼 金色葡萄球菌 青霉素 抗菌素 耐药 眼眶蜂窝织炎 群体性
摘 要：PURPOSE: To describe bilateral blindness resulting from infection with community-acquired methicillin-resistant Staphylococcus aureus (MRSA). DESIGN: Observational case report. METHODS: A 44- year-old man developed proptosis, ptosis, ophthalmoplegia, and no light perception vision after attempting to lance a nasal pustule. A nasal culture grew MRSA. Imaging showed bilateral orbital cellulitis, pansinusitis, and cavernous sinus thrombosis. The right fundus showed severe ischemia, but the left fundus was essentially normal. RESULTS: Despite initiation of appropriate antibiotics early in the course of infection, the patient lost sight in both eyes. Surgical drainage of the paranasal sinuses and use of intravenous corticosteroids and heparin led to the resolution of orbital cellulitis. CONCLUSIONS: MRSA orbital cellulitis can progress to irreversible blindness despite antibiotic treatment. A new, community-acquired clone of this organism has exhibited increased potential for tissue invasion.
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