Therapy for <i>H.</i><i>pylori</i>: Current concepts

作     者：Giulia Fiorini Angelo Zullo Valentina Castelli Chiara Ricci Giovanna Lo Re Ilaria Saracino Cristina Zaccaro Federico Maria Verardi Alessandra Reggi Dino Vaira 

作者机构：Department of Clinical and Surgical Science S.Orsola-Malpighi Hospital University of Bologna Bologna Italy Department of Internal Medicine Aging and Kidney Disease Alma Mater Studiorum University of Bologna Bologna Italy Gastroenterology and Digestive Endoscopy “Nuovo Regina Margherita” Hospital Rome Italy Gastroenterology Unit University of Brescia Brescia Italy 

出 版 物：《Open Journal of Gastroenterology》 (肠胃病学期刊（英文）)

年 卷 期：2013年第3卷第1期

页      面：38-41页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Helicobacter pylori Sequential Therapy Eradication 

摘      要：Helicobacter pylori plays an important role in the pathogenesis of chronic active gastritis, peptic ulcer and gastric mucosa-associated lymphoid tissue-lymphoma, and is also involved in carcinogenesis of the stomach. Since now no current first-line therapy is able to cure the infection in all treated patients. We evaluated data on the most successful therapy regimens—sequential, concomitant and quadruple therapies—and on the standard therapy available for H. pylori eradication. When therapy fails several factors may be involved: we reviewed both bacterial and host factors that can affect the eradication and that can be involved in therapeutic management of the H. pylori infection.