Design,synthesis and insecticidal activity of novel anthranilic diamides with benzyl sulfide scaffold

作     者：Yin-Bo Chen Ji-Ling Li Xu-Sheng Shao Xiao-Yong Xu Zhong Li 

作者机构：Shanghai Key Lab of Chemistry BiologySchool of PharmacyEast China University of Science and Technology 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2013年第24卷第8期

页      面：673-676页

核心收录：

学科分类：090403[农学-农药学(可授农学、理学学位）] 09[农学] 0904[农学-植物保护] 

基　　金：supported by National Basic Research Program of China(973 Program,No.2010CB126100) National High Technology Research and Development Program of China (863 Program,No.2011AA10A207) supported by National Key Technology R&D Program of China(No. 2011BAE06B01) 

主　　题：Anthranilic diamides Benzyl sulfide Synthesis Insecticidal activity 

摘      要：A series of novel anthranilic diamides with benzyl sulfide scaffold were synthesized,in which N-pyridylpyrazole moiety generally regarded as key pharmacophore was *** target compounds were characterized by ~1H NMR,^（13）C NMR,^（19）F NMR and *** preliminary bioassays indicated that half of the title compounds were endowed with good insecticidal activities against armyworm（Mythimna sepatara） at the concentration of 500 mg/L,Exhilaratingly,the synthesized compound 3a was also active against Tetranychus cinnabarinus at 100 mg/*** difference in activities between the target compounds was influenced by the substituents,which provided some hints for further investigation on structure modifications.