Graphdiyne oxide enhances the stability of solid contact-based ionselective electrodes for excellent in vivo analysis

作     者：Lijun Zhao Ying Jiang Jie Hao Huan Wei Wei Zheng Lanqun Mao 

作者机构：Beijing National Laboratory for Molecular SciencesKey Laboratory of Analytical Chemistry for Living BiosystemsInstitute of Chemistrythe Chinese Academy of SciencesBeijing 100190China Institute of Surface/Interface Science and TechnologyKey Laboratory of Superlight Material and Surface Technology of Ministry of EducationCollege of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China University of Chinese Academy of SciencesBeijing 100049China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2019年第62卷第10期

页      面：1414-1420页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China (21790390, 21790391, 21621062, 21435007) for Lanqun Mao the National Basic Research Program of China (2016YFA0200104) the Chinese Academy of Sciences (QYZDJ-SSW-SLH030) 

主　　题：in vivo analysis graphdiyne oxide solid-state ion selective electrodes water layer 

摘      要：Quantitively and stably tracking ion dynamics in the living brain of animals is essential to understanding many physiological and pathological ***-state ion-selective electrodes(ISEs)are powerful tools for monitoring the dynamic change of ions at physiological concentration range;however,the unintentional accumulation of an aqueous layer at the ion selective membrane/solid contact interface compromises the electrode potential stability,limiting its in vivo ***,using manganese dioxide(MnO2)and potassium ISE(K-+ISE)as model solid contact and ISEs,we demonstrate for the first time that graphdiyne oxide(GDYO)can enhance the potential stability of solid contact-based *** results suggest that the intrinsic structural and hydrophobic features of GDYO,plays a key role in impeding and stabilizing the formation of water *** GDYO-MnO2 acting as the solid contact,the K-+ISE displays an excellent short-term potential stability and maintains great selectivity,achieving reliable K+sensing at the animal *** GDYO-based strategy is generalizable to different ISEs and does not require complicated processing steps,paving an exciting opportunity for in vivo ion recognition and sensing.