Protein adsorption on materials surfaces with nano-topography

作     者：SONG Wei CHEN Hong 

作者机构：School of Materials Science and Engineering Wuhan University of Technology Wuhan 430070 China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology Wuhan 430070 China 

出 版 物：《Chinese Science Bulletin》 (CHINESE SCIENCE BULLETIN)

年 卷 期：2007年第52卷第23期

页      面：3169-3173页

核心收录：

学科分类：08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 

基　　金：Supported by the National Natural Science Foundation of China (Grant Nos. 90606013 and 20634030) the Ministry of Science and Technology (Grant No. 107080) 

主　　题：蛋白质 吸附 材料表面 地形图 生物适应性 

摘      要：Protein adsorption behavior on the surfaces of biomedical materials is highly related to the biocom- patibility of the materials. In the past, numerous research reports were mainly focused on the effect of chemical components of a material’s surface on protein adsorption. The effect of surface topography on protein adsorption, the topic of this review, has recently received keen interest. The influence of surface nano-topographic factors, including roughness, curvature and geometry, on protein adsorption as well as the protein adsorption behavior, such as the amount of protein adsorbed, the activity and morphology of adsorbed protein, is introduced.