Capillary electrophoresis with direct chemiluminescence detection for the analysis of catecholamines in human urine
Capillary electrophoresis with direct chemiluminescence detection for the analysis of catecholamines in human urine作者机构：College of Chemistry and Chemical Engineering Xinyang Normal University Xinyang 464000 China
出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)
年 卷 期：2007年第18卷第4期
页 面：452-454页
核心收录：
学科分类：1010[医学-医学技术（可授医学、理学学位）] 10[医学]
基 金：the National Natural Science Foundation of China (No. 20575056) the 0utstanding Youth Science Foundation of Henan Province (No. 04120001300) Henan Innovation Project for University Research Talents (No. 2005126)
主 题：Capillary electrophoresis Catecholamines Chemiluminescence detection Urine
摘 要：A rapid and sensitive method for the analysis of three catecholamines by capillary electrophoresis （CE） with direct chemiluminescence （CL） detection is described. The detection limits （S/N= 3） were 1.3 × 10^-8 g/mL for isoprenaline, 1.0 × 10^-8g/mL for epinephrine and 2.8 × 10^-8 g/mL for dopamine. The proposed method was successfully applied to the analysis of catecholamines in urine samples of cigarette smokers and nonsmokers. The results showed that there is a close relation between the release of dopamine in human body fluids and cigarette smoking/nonsmoking.
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