Incidence, distribution of histological subtypes and primary sites of soft tissue sarcoma in China

作     者：Zhixun Yang Rongshou Zheng Siwei Zhang Hongmei Zeng He Li Wanqing Chen 

作者机构：National Cancer Center National Clinical Research Center for Cancer Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College 

出 版 物：《Cancer Biology & Medicine》 (癌症生物学与医学（英文版）)

年 卷 期：2019年第16卷第3期

页      面：565-574页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by CAMS Innovation Fund for Medical Sciences (CIFMS) (Grant No.2016-12M-2-004) Ministry of Science and Technology (Grant No.2014FY121100) 

主　　题：Soft tissue sarcoma incidence gastrointestinal stromal tumor epidemiology China 

摘      要：Objective: Soft tissue sarcomas(STSs) are rare malignancies deriving from *** this study, we reported the epidemiology of STS in China using population-based cancer registry ***: In 2017, qualified data from 339 cancer registries were included in the national *** STS cases were retrieved based on the morphological and topographical codes of International Classification of Diseases for Oncology, and were categorized into different histological subtypes and primary sites *** new STS cases were estimated using incidence rate of STS and the national population, and were reported for gastrointestinal stromal tumor(GIST) and STSs other than GIST separately by sex and *** of histological subtypes and primary sites of STS were calculated, as well as primary sites of ***: Approximately 39,900 new STS cases occurred nationwide in China in 2014, accounting for 1.05% of overall cancer *** crude incidence rate was 2.91/100,000 and generally increased with *** overall female predilection was *** was the most common histological subtype, followed by nerve sheath tumor and malignant peripheral nerve sheath tumor,leiomyosarcoma, liposarcoma, and *** 67.5% of GIST occurred in stomach while 1.4% were recorded outside the gastrointestinal ***, subcutaneous and other soft tissues were the most common primary site, of which extremities were the major ***: The burden of STS is not serious in China ***, due to their histological and topographical complexity, STSs should not be unnoticed, and more basic and clinical studies should focus on STSs.