Static and 50 Hz Electromagnetic Fields Effects on Human Neuronal-Like Cells Vibration Bands in the Mid-Infrared Region
Static and 50 Hz Electromagnetic Fields Effects on Human Neuronal-Like Cells Vibration Bands in the Mid-Infrared Region作者机构：不详
出 版 物：《Journal of Electromagnetic Analysis and Applications》 (电磁分析与应用期刊（英文）)
年 卷 期：2011年第3卷第2期
页 面：69-78页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Static Magnetic Field 50 Hz Electromagnetic Field Neuronal-Like Cells FTIR Spectroscopy
摘 要：Human neuronal-like cells were exposed to static and 50 Hz electromagnetic fields at the intensities of 2 mT and 1 mT, respectively. The effects of exposure were investigated in the mid-infrared region by means of Fourier self deconvolu-tion spectroscopic analysis. After exposure of 3 hours to static and 50 Hz electromagnetic fields, the vibration bands of CH2 methilene group increased significantly after both exposures, suggesting a relative increase of lipid related to conformational changes in the cell membrane due to electromagnetic fields. In addition, PO2- stretching phosphate bands decreased after both exposures, suggesting that alteration in DNA/RNA can be occurred. In particular, exposure of 3 hours to 50 Hz electromagnetic fields produced significant increases in β-sheet contents in amide I, and around the 1740 cm?1 band assigned to non-hydrogen-bonded ester carbonyl stretching mode, that can be related to unfolding processes of proteins structure and cells death. Further exposure up to 18 hours to static magnetic field produced an increase in β-sheet contents as to α-helix components of amide I region, as well.
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