Preimplantation genetic diagnosis and the biopsy technique: Important considerations
Preimplantation genetic diagnosis and the biopsy technique: Important considerations作者机构：Centre for Reproductive Medicine European Hospital Via Portuense Rome Italy
出 版 物：《Advances in Reproductive Sciences》 (生殖科学（英文）)
年 卷 期：2013年第1卷第2期
页 面：7-14页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Preimplantation Genetic Diagnosis Screening Polar Body Embryo Blastocyst Biopsy
摘 要：Preimplantation genetic diagnosis allows to test the genetic status of embryos prior to implantation. In order to obtain genetic material, on which carry out a genetic diagnosis, a procedure named embryo biopsy is required. In the last two decades, embryo biopsy at the cleavage stage has been the mostly performed procedure. However, recently, alternative methods allowing the retrieval of a larger number of cells (blastocyst stage biopsy), or representing a valid alternative to overcome ethical issues (polar body biopsy) have obtained increasing consensus. This article reviews different methods of embryo biopsy and points out their positive and negative aspects.
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