Three-dimensional structure determination of capsid of Aedes albopicus C6/36 cell densovirus

作     者：CHENG Lingpeng1, CHEN Senxiong1, Jenifer M. Brannan2, Joanita Jakana3, ZHANG Qinfen1, Z. H. Zhou2 & ZHANG Jingqiang1 1. State Key Laboratory for Bio-control, Zhongshan University, Guangzhou 510275, China 2. Department of Pathology, Medicine University of Texas-Huston Medical School, Huston, TX77030, USA 3. National Center for Macromolecular Imaging, Baylor College of Medicine, Houston, TX77, USA 

作者机构：State Key Laboratory for Bio-control Zhongshan University Guangzhou 510275 China Department of Pathology Medicine University of Texas-Huston Medical School Huston TX77030 USA National Center for Macromolecular Imaging Baylor College of Medicine Houston TX77 USA 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2004年第47卷第3期

页      面：224-228页

学科分类：0710[理学-生物学] 07[理学] 09[农学] 

基　　金：This work was supported by the National Natural Science Foundation of China(Grant No.10274106) NIH(USA) the Welch Foundation the American Heart Association JMB was an HAMBP trainee supported by NIH(5T32GM08280) 

主　　题：electron cryomicroscopy, three-dimensional reconstruction, Aedes albopictus densovirus. 

摘      要：The three-dimensional structure of capsid of Aedes albopictus C6/36 densovirus was determined to 14- resolution by electron cryomicroscopy and computer reconstruction. The triangulation number of the capsid is 1. There are 12 holes in each triangular face and a spike on each 5-fold vertex. The validity of the capsid and nucleic acid densities in the reconstructions was discussed.