Nyctanthes arbor-tristis L.叶甲醇提取物的总酚含量及体外抗氧化作用(英文)

作     者：Savarimuthu Michael. J Kalirajan. A Padmalatha. C A.J.A. Ranjit Singh 

作者机构：Department of Zoology Sri Paramakalyani College M S University Department of Zoology Rani Anna Government College for Women M S University 

出 版 物：《中国天然药物》 (Chinese Journal of Natural Medicines)

年 卷 期：2013年第11卷第5期

页      面：484-487页

核心收录：

学科分类：0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 1005[医学-中医学] 100706[医学-药理学] 1002[医学-临床医学] 0703[理学-化学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：University Grants Commission  UGC 

主　　题：Antioxidant DPPH -OH NO Superoxide radical-scavenging activity Nyctanthes arbor-tristis 

摘      要：AIM:To investigate the in vitro antioxidant activity and total phenolic content of the methanolic leaf extract of Nyctanthes arbor-tristis L.(NA).METHODS:The sample was tested using five in vitro antioxidant methods(1,1-diphenyl-2-picryl hydrazine radical scavenging activity(DPPH),hydroxyl radical-scavenging activity(-OH),nitric oxide scavenging activity(NO),superoxide radical-scavenging activity,and total antioxidant activity)to evaluate the in vitro antioxidant potential of NA and the total phenolic content(Folin-Ciocalteu method).The extract showed good free radical scavenging property which was calculated as an ***:IC50(Half maximal inhibitory concentration)of the methanolic extract was found to be 57.93μg·mL for DPPH,98.61μg·mL for-OH,91.74μg·mL for NO,and 196.07μg·mL for superoxide radical scavenging *** antioxidant capacity of the extract was found to be(1198±24.05)mg ascorbic acid for the methanolic *** radical scavenging activity observed in the extracts of NA showed a concentration-dependent *** in vitro scavenging tested for free radicals was reported to be due to high phenolic content in the leaf *** leaf extract of NA showed the highest total phenolic content with a value of78.48±4.2 equivalent mg TAE/g(tannic acid equivalent).CONCLUSIONS:***-tristis leaf extract exhibited potent free radical scavenging *** finding suggests that ***-tristis leaves could be a potential source of natural antioxidant.