Regulation of immune cell responses by semaphorins and their receptors
Regulation of immune cell responses by semaphorins and their receptors作者机构：Department of Immunopathology Research Institute for Microbial Diseases Osaka University Suita Osaka Japan World Premier International Immunology FrontierResearch Center Osaka University Suita Osaka Japan
出 版 物：《Cellular & Molecular Immunology》 (中国免疫学杂志（英文版）)
年 卷 期：2010年第7卷第2期
页 面：83-88页
核心收录：
学科分类：0710[理学-生物学] 071010[理学-生物化学与分子生物学] 090602[农学-预防兽医学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 09[农学] 0906[农学-兽医学]
基 金：Takeda Science Foundation, TSF Uehara Memorial Foundation Japan Society for the Promotion of Science, KAKEN Ministry of Education, Culture, Sports, Science and Technology, MEXT Japan Science and Technology Agency, JST Ministry of Health, Labour and Welfare, MHLW National Institute of Biomedical Innovation, NIBIO
主 题：semaphorin immune regulation immune cell trafficking tumorigenesis autoimmune diseases
摘 要：Semaphorins were originally identified as axon guidance factors involved in the development of the neuronal system. However, accumulating evidence indicates that several members of semaphorins, so-called ＇immune semaphorins＇, are crucially involved in various phases of immune responses. These semaphorins regulate both immune cell interactions and immune cell trafficking during physiological and pathological immune responses. Here, we review the following two functional aspects of semaphorins and their receptors in immune responses： their functions in cell-cell interactions and their involvement in immune cell trafficking.
维普期刊数据库