应用达珠单抗(人源化抗白介素-2受体α抗体)新疗法治疗由成人T细胞白血病/淋巴瘤导致的Sézary样综合征
Novel treatment of Sézary-like syndrome due to adult T-cell leukaemia/lymphoma with daclizumab (humanized anti-interleukin-2 receptor α antibody)作者机构:Department of HaematologyKing's College Hospital Denmark Hill London SE5 9RS United Kingdom
出 版 物:《世界核心医学期刊文摘(皮肤病学分册)》 (Digest of the World Core Medical JOurnals:Dermatology)
年 卷 期:2006年第2卷第11期
页 面:49-49页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:淋巴瘤 zary 受体α 人源化 持续完全缓解 红皮病
摘 要:We describe a patient with erythrodermic adult T-cell leukaemia/ lymphoma resistant to multiple systemic therapies who, on the commencement of daclizumab, a humanized anti-interleukin-2 receptor antibody, developed a rapid and sustained complete response with resolution of previously debilitating erythroderma, suggesting significant activity of this agent in this disease process.