Effects of ethanol extract of leaves of Helianthus annus on the fecundity of Wistar rats

作     者：Ejebe Daniel Emamuzo Siminialayi Iyeopu Miniakiri Emudainohwo Joseph Oghenebrorie Tedwin Kagbo Hope Delesi Amadi Precious 

作者机构：Department of PharmacologyDelta State University AbrakaNigeria Department of PharmacologyUniversity of Port HarcourtNigeria Institute of Science Laboratory and TechnologyDelta State UniversityAbraka Nigeria 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2010年第3卷第6期

页      面：435-438页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

主　　题：Ethanol extract Helianthus annus Leaves Fecundity Rats 

摘      要：Objective:To evaluate the effects of ethanol extract of leaves of Helianthus annus(***) on the fecundity of Wistar ***:Forty(20 male and 20 female) Wistar rats,grouped into control,ethanol extract treated rats and untreated,were used for the *** rats had 0.5 g/kg of ethanol extract orally for 2 weeks;control rats had 5%alcoholic water(solvent);and untreated rats had their normal feed and clean drinking *** treatment,the animals were sub-grouped into 5 mating groups to observe the coital frequency,pregnancy rate and average number of pups per group in ***:The results showed that coital frequency was unaffected by the extract treatment but pregnancy rate and number of pups per rat and per group were reduced significantly in groupsⅡ,ⅢandⅣcompared to those of groupⅠandⅤrats which were not treated with the ethanol extract of leaves of ***:The histodegenerative in the gonads reportedly induced by this ethanol extract in previous studies may be responsible for the reduced fecundity observed in treated adult rats.