Study on the Synthesis of Metabolite CM2 of Clausenamide
Study on the Synthesis of Metabolite CM2 of Clausenamide作者机构:Institute of Materia MedicaChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050
出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))
年 卷 期:2003年第14卷第4期
页 面:338-340页
核心收录:
学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
基 金:This work was supported by the National Natural Science Foundation of China. ( No.29790121)
主 题:Metabolite clausenamide dehydration dihydroxylation deacylation.
摘 要:Synthesis of the optically active metabolite of clausenamide CM2 (3, 5-dihydroxy- 5-(a-hydroxylbenzyl)-1-methyl-4-benzylpyrrolidin-2-one) from 3-O-acetyl- clausenamide was described.