Palladium-Catalyzed Cyclocarbonylation of 2-Halobenzaldehyde and Hydrazines： A Facile Synthesis of 2-Aminoisoindolin-l-ones
Palladium-Catalyzed Cyclocarbonylation of 2-Halobenzaldehyde and Hydrazines： A Facile Synthesis of 2-Aminoisoindolin-l-ones作者机构：Department of Chemistry Zhejiang University Hangzhou Zhejiang 310027 China
出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)
年 卷 期：2013年第31卷第2期
页 面：182-186页
核心收录：
学科分类：081702[工学-化学工艺] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
基 金：the National Natural Science Foundation of China
主 题：cyclocarbonylation 2-aminoisoindolin-l-ones multicomponent reactions heterocycles
摘 要：An efficient procedure for the synthesis of 2-aminoisoindolin-l-ones via a palladium-catalyzed three-component reaction of 2-halobenzaldehydes, hydrazines and carbon monoxide is reported. This cyclocarbonylation process can be performed smoothly under 1 atmospheric pressure of carbon monoxide to afford 2-aminoisoindolin- 1-ones in moderate to excellent yields.
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