Total saponins of Panax notoginseng protected rabbit iliac artery against balloon endothelial denudation injury

作     者：Si-wei CHEN, Xiao-hong LI, Kai-he YE, Zuo-feng JIANG, Xian-da RENDepartment of Cardiology, the 4th Affliated Hospital of Ji-nan University, Department of Clinical Pharmacology, Pharmacy College, Ji-nan University, Guangzhou 510632, China 

出 版 物：《Acta Pharmacologica Sinica》 (中国药理学报(英文版))

年 卷 期：2004年第9期

页      面：49-54页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：SupportedbyScienceFoundationofGuangdongProvincialTraditionalMedicineCommittee No101038 

主　　题：Panax ginseng saponins balloon dilatation restenosis extracellular matrix vascular smooth muscle 

摘      要：AIM: To investigate whether total Panax notoginseng saponins (PNS) could protect endothelium of rabbit iliac artery against balloon endothelial denudation (BED) injury. METHODS: The morphology changes of the endothelium were observed with scanning electron microscope (SEM) and hematoxylin and eosin stain after BED of rabbit iliac artery at 0,4,6, and 8 week respectively. Vascular endothelial growth factor (VEGF) and matrix