Meperidine-induced Seizure in an Adult Patient with Lung Lesions

作     者：Wei Luo Ya-Lun Li Qi YU Yi-Shi Li Shu-Liang Guo Luo Wei;Li Ya-Lun;Yu Qi;Li Yi-Shi;Guo Shu-Liang

作者机构：Department of Respiratory and Critical Care Medicine The First Affiliated Hospital of Chongqing Medical University Chongqing 400016 China Department of Respiratory and Critical Care Medicine West China Hospital Sichuan University Chengdu Sichuan 610041 China Department of Pediatrics The Leshan People's Hospital Leshan Sichuan 614000 China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2016年第129卷第3期

页      面：370-371页

核心收录：

学科分类：0710[理学-生物学] 090601[农学-基础兽医学] 071010[理学-生物化学与分子生物学] 1002[医学-临床医学] 07[理学] 09[农学] 0906[农学-兽医学] 

基　　金：supported by the National Key Clinical Specialist Construction Programs of China 

主　　题：Meperidine pethidine Lesions 

摘      要：To the Editor： Meperidine, also known as pethidine, is one of the most commonly prescribed opioid analgesics.Meperidine exerts high central nervous system depressant effects through producing prolonged activation of opioid receptors （μ-receptor）.We described a rare case of generalized tonic-clonic seizures after intravenous （Ⅳ） injection of meperidine for bronchoscopy premedication in a patient with a lung lesion who lacked a prior history of seizures.