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Colorectal cancer surveillance in inflammatory bowel disease:Practice guidelines and recent developments

Colorectal cancer surveillance in inflammatory bowel disease:Practice guidelines and recent developments

作     者:William T Clarke Joseph D Feuerstein 

作者机构:Department of Medicine and Division of Gastroenterology Beth Israel Deaconess Medical Center Harvard Medical School 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2019年第25卷第30期

页      面:4148-4157页

核心收录:

学科分类:10[医学] 

主  题:Inflammatory bowel disease Colorectal cancer screening Ulcerative colitis Crohn’s disease Colonoscopy Chromoendoscopy 

摘      要:Patients with long-standing inflammatory bowel disease(IBD)involving at least 1/3 of the colon are at increased risk for colorectal cancer(CRC).Advancements in CRC screening and surveillance and improved treatment of IBD has reduced CRC incidence in patients with ulcerative colitis and Crohn’s *** cases of CRC are thought to arise from dysplasia,and recent evidence suggests that the majority of dysplastic lesions in patients with IBD are visible,in part thanks to advancements in high definition colonoscopy and *** practice guidelines have supported the use of chromoendoscopy with targeted biopsies of visible lesions rather than traditional random *** are encouraged to endoscopically resect visible dysplasia and only recommend surgery when a complete resection is not *** technologies such as virtual chromoendoscopy are emerging as potential tools in CRC *** with IBD at increased risk for developing CRC should undergo surveillance colonoscopy using new approaches and techniques.

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