咨询与建议

看过本文的还看了

相关文献

该作者的其他文献

文献详情 >Further antiplasmodial effects... 收藏

Further antiplasmodial effects of the aqueous extract of cymbopogon citratus stapf (lemon grass) against plasmodium berghei in Swiss albino mice

Further antiplasmodial effects of the aqueous extract of cymbopogon citratus stapf (lemon grass) against plasmodium berghei in Swiss albino mice

作     者:DV Dapper IM Siminialayi OO Ebong 

作者机构:Department of PharmacologyFaculty of Basic Medical SciencesCollege of Health SciencesUniversity of Port HarcourtPMB 5323Port HarcourtNigeria Department of Human Physiology and Malaria Research UnitFaculty of Basic Medical SciencesCollege of Health SciencesUniversity of Port HarcourtPMB 5323Port HarcourtNigeria 

出 版 物:《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志(英文版))

年 卷 期:2008年第1卷第3期

页      面:7-12页

核心收录:

学科分类:1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

主  题:cymbopogon citratus stapf antiplasmodial activity P.berghei 

摘      要:Lemon grass(Cymbopogon citratus Stapf) is a popular alternative to western medicines for a number of conditions, including fevers,muscle soreness and superficial infections in *** addition to its already reported suppressive effects against *** infection,this study sought to determine its repository and blood schizonticidal activities in established *** infection using Swiss albino mice as *** weighing on average, between 15 and 25g were given 103mg/kg,155mg/kg and 310mg/kg/day of the crude aqueous extract of cymbopogon citratus stapf,in the 4-day test,24-hour Rane test and 72-hour Rane *** effects of these doses of the extract were then compared with chloroquine(5mg/kg/day) and sulphadoxine/pyrimethamine (3mg/kg/day).We report an average percentage suppressive repository activity of 65.8%for the extract at a dose of 310mg/kg and a blood schizonticidal activity that increased from 68.33%in the 24-hour Rane test to 92%in the 72-hour Rane test for the same dose of *** crude aqueous extract of *** stapf thus has significant repository and blood schizonticidal activities against established *** infection in Swiss albino mice compare to that of pyrimethamine and sulphadoxine/pyrimethamine respectively.

读者评论 与其他读者分享你的观点

用户名:未登录
我的评分