Fluorescent and colorimetric immunoassay of nuclear matrix protein 22 enhanced by porous Pd nanoparticles

作     者：Wenyun Zhuge Xiaofeng Tan Ruyue Zhang He Li Gengxiu Zheng 

作者机构：School of Chemistry and Chemical EngineeringUniversity of Jinan 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2019年第30卷第6期

页      面：1307-1309页

核心收录：

学科分类：07[理学] 0703[理学-化学] 

基　　金：the Natural Science Foundation of Shandong Province(No.ZR2017MB017) 

主　　题：Nuclear matrix protein 22 Porous Pd nanoparticles ELISA Colorimetric Fluorescence 

摘      要：A modified ELISA realizing fluorescent and colorimetric immunoassay of nuclear matrix protein 22 (NMP 22) was developed based on porous Pd nanoparticles. The unique structure and excellent enzyme mimetic activity of porous Pd nanoparticles favor to oxidize o-phenylenediamine (OPD) into 2,3-phenazinediamine (oxOPD) by H2O2, producing colorimetric and fluorescence dual-readout signal for the detection of NMP 22. The developed immunoassay method will offer great potential in clinical research and diagnostic applications.