Surveillance of antibiotic sensitivity pattern in chronic suppurative otitis media of an Indian teaching hospital

作     者：Mahesh Chandra Sahu Santosh Kumar Swain Sahu Mahesh Chandra;Swain Santosh Kumar

作者机构：IMS and SUM HospitalSiksha'O'Anusandhan UniversityK8KalinganagarBhubaneswar751003OdishaIndia Department of OtorhinolaryngologyIMS and SUM HospitalSiksha'O'Anusandhan UniversityK8KalinganagarBhubaneswar751003OdishaIndia 

出 版 物：《World Journal of Otorhinolaryngology-Head and Neck Surgery》 (世界耳鼻咽喉头颈外科杂志（英文）)

年 卷 期：2019年第5卷第2期

页      面：88-94页

学科分类：1003[医学-口腔医学] 1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：NPDF Department of Science and Technology, Ministry of Science and Technology, India, डीएसटी Science and Engineering Research Board, SERB 

主　　题：Antibiotics Chronic suppurative otitis media Gram negative bacteria ESBL MBL 

摘      要：Introduction:Chronic suppurative otitis media (CSOM) is a common problem in worldwide and untreated CSOM leads to fatal complications like facial nerve paralysis,lateral sinus thrombosis,labyrinthitis,meningitis and brain abscess in developing country like ***:To isolate causative bacteria and antibiotic sensitivity pattern for CSOM and to know the prevalence of extended spectrum beta lactamases (ESBL) and Metallobetalactamases (MBL) in CSOM ***:A total of 500 ear swabs of clinical suspected CSOM patients were cultured on specific cultured medium and identified the bacteria with conventional *** all the identified bacteria were subjected with specific antibiotics by the Kirby-Bauer s method to know the resistance pattern of *** and MBL strains were detected by double disc diffusion ***:A total of 384 bacteria were isolated from 500 CSOM patients,among them 86 *** (22.40%),112 Staphylococcus aureus (29.17%),53 *** (13.80%),32 *** (18%),26 *** (6.77%),24 *** (6.25%),23 *** (5.99%),18 *** (4.69%) and 10 *** (2.60%) identified with conventional *** antibiotic disc diffusion methods 74.22% ESBL strains and 9.90%MBL strains were *** resistant strains of *** (86/384,22.40%) were more prevalent than those of *** (112/384,29.17%) and other bacteria in ear *** and vancomicin could control to gram negative bacteria and gram positive bacteria ***:Continuous and periodic evaluation of microbiological profile and antimicrobial sensitivity pattern of bacterial is essential for optimum management of CSOM patients.