Antiphospholipid syndrome:a survey of clinical characters in ten cases
Antiphospholipid syndrome:a survey of clinical characters in ten cases作者机构:DepartmentofInternalMedicineFirstAffiliatedHospitalCollegeofMedicineZhefiangUniversityHangzhou310003China
出 版 物:《Journal of Zhejiang University Science》 (浙江大学学报(自然科学英文版))
年 卷 期:2003年第4卷第5期
页 面:616-619页
核心收录:
学科分类:0810[工学-信息与通信工程] 100208[医学-临床检验诊断学] 1002[医学-临床医学] 0805[工学-材料科学与工程(可授工学、理学学位)] 0812[工学-计算机科学与技术(可授工学、理学学位)] 10[医学]
摘 要:Objective: To gain further understanding of the antiphospholipid syndrome(APS) . Methods : Analysing clinical and laboratory data on ten cases of APS. Results: Thrombocytopenia appeared in all *** thrombi of limbs appeared in five eases and neurological abnormalities in two cases. Renal impairments were found in three cases. One case manifested left renal venous thrombi and the other two cases thrombotic microangiopathy. Budd-Chiari syndrome was found in one case. One of the ten cases was catastrophic APS(CAPS) presented as acute diffuse swelling, cyanosis, pain, ischemia and necrosis in fingers and limbs,recurrem shock, ascites, hepatic and respiratory dysfunction. Anticoagulams and corticosteroids could be effective for dealing with APS. It was critical to treat catastrophic APS with anticoagulants or plasmapheresis as early as possible. Conclusions: APS shows variable manifestations for good prognosis, but catastrophic APS has fatal risk. The main treatment for APS is the use of anticoagulams and immunosuppressives.